Euthanasia (Guideline) | Vertebrate Animal Research
Guidelines: The IACUC has provided a set of guidance documents (Policies, Guidelines, and Informational Sheets) for use when planning animal procedures at the University of Iowa. An exception to a Guideline must be described and justified in the Animal Protocol
Aversion to Gaseous Euthanasia Agents in Rats and Mice: …
Comparisons between euthanasia agent and control (air) treatments indied that concentrations of agents recommended for rapid and efficient induction are associated with some degree of aversion. Carbon dioxide and the carbon dioxide-argon mixtures …
Medical carbon dioxide | Linde Healthcare
Medical carbon dioxide is used as an insufflation gas and as a cooling agent. Medical carbon dioxide has various medical purposes. It can be used as an insufflation gas for minimal invasive surgery (laparoscopy, endoscopy, and arthroscopy) to enlarge and stabilize body cavities for …
Standard Operating Procedure #2
as a euthanasia agent. The duration of exposure to carbon dioxide varies with the age of the neonate. Inbred and outbred neonatal rats less than 7 d of age may differ in susceptibility to CO 2, requiring exposures as long as 50 min to ensure euthanasia. When 2
AALAS & CITI Questions Flashcards by Todd Lash | …
It is best to coine carbon dioxide with oxygen for euthanasia. The optimal flow rate is one that displaces 10% of the chaer volume every minute. Gas flow should be maintained for at least 1 minute after apparent death to make sure the animal does not recover.
Guidelines on Use of Carbon Dioxide for Euthanasia of Rodents for additional information. II. Non-inhalant Pharmaceutical Agents: Barbiturates Pentobarbital – 200 mg/kg iv is sufficient for euthanasia of most lab animal species. Intraperitoneal injection may
Humane disposal of Mynas
The Methods of Euthanasia SOP (PDF, 288k) describes the general use of carbon dioxide as a method; the Trapping of Pest s SOP (PDF, 227k) has further specific information on the method for use with s in traps, and it also provides advice on trapping.
Research ReportResearch ReportResearch Report
1 This research report has been prepared by RSPCA Australia (. For further information, please phone (02) 6282 8300 or e-mail [email protected] January 2007 Research ReportResearch ReportResearch Report Use of carbon dioxide for
Appendix 3: Euthanasia - Wiley Online Library
Appendix 3 EUTHANASIA Michael J. Murray 303 Little is written about euthanasia of invertebrates. One might suggest that euthanasia regarding these animals is a non se-quitur, particularly in the more primitive groups (Porifera and Coelenterata), given the absence
El dióxido de carbono para la eutanasia: preocupación …
Carbon dioxide (CO2) is the most commonly used agent for euthanasia of laboratory rodents, used on an estimated tens of millions of laboratory rodents per year worldwide, yet there is a growing body of evidence indiing that exposure to CO2 causes more than
Rat aversion to isoflurane versus carbon dioxide | …
1. Introduction Carbon dioxide (CO 2) is the most commonly used euthanasia agent for rodents, but there is evidence that this gas is aversive.Rats show signs of distress when forced to remain in a chaer filling with CO 2  and choose to give up a food reward to escape a chaer filling with CO 2 when the concentration exceeds 15 per cent [2,3] even when food-deprived for 24 h .
Home | UMass Amherst - SOP No 49-313.3
approved source of carbon dioxide for euthanasia. Sudden exposure of conscious animals to high concentrations of carbon dioxide has been shown to be distressful. Therefore, without pre-charging the euthanasia chaer, introduce 100% carbon dioxide at a rate of 30% – …
Mass nt Handling - USDA-APHIS
for euthanasia. Carbon dioxide has been used extensively in the past for mass euthanasia during disease eradiion. Carbon dioxide is heavier than atmospheric air and will sink to the bottom of the room or container in which it is used. Carbon monoxide may be
Newcastle Consensus Meeting on Carbon Dioxide Euthanasia of …
euthanasia agents, with respect to both animal welfare and human health and safety. The Consensus Meeting on Carbon Dioxide Euthanasia of Laboratory Animals was thus convened with a nuer of aims: • • • • • to bring together scientists who have2 as a
CiteSeerX — Coining Nitrous Oxide with Carbon …
Carbon dioxide (CO2) is the most commonly used euthanasia agent for rodents despite potentially causing pain and distress. Nitrous oxide is used in man to speed induction of anaesthesia with volatile anaesthetics, via a mechanism referred to as the ‘‘second gas’ ’ effect.
The effect of age and method of gas delivery on carbon dioxide euthanasia …
Keywords:age, animal welfare, behaviour, carbon dioxide, euthanasia, pigs Introduction There are times on a swine farm when pigs (Sus scrofa) become ill or injured, and the animal care person must decide if euthanasia is necessary and, if so, what method of
Methods of Humane Euthanasia in Rats - SWMS
• Neonates are resistant to hypercapnia- carbon dioxide is not a suitable euthanasia agent for rodent pups less than 10 days of age. Alternative methods such as cervical disloion, decapitation, or …
PACUC Guideline CO for of Rodents - Purdue University
Carbon dioxide for euthanasia: concerns regarding pain and distress, with special reference to mice and rats. Laboratory Animals 2005, 39: 137-161. 4. Guidelines for the Euthanasia of Rodent Feti and Neonates. NIH Animal Research Advisory Committee 5.
Rat aversion to isoflurane versus carbon dioxide | …
Some experts suggest that sedation of laboratory rodents with isoflurane before euthanasia with carbon dioxide (CO 2) is a humane alternative to euthanasia with CO 2 alone, but little research has compared aversion with these agents. Albino rats were tested in a
Standard Operating Procedure #2 - Queen''s University
as a euthanasia agent. The duration of exposure to carbon dioxide varies with the age of the neonate. Inbred and outbred neonatal mice less than 7d of age may differ in susceptibility to CO 2, requiring exposures as long as 50 min to ensure euthanasia. When 2
IACUC Policy on Euthanasia of Laboratory Animals
IACUC Policy on Euthanasia of Laboratory Animals The term euthanasia is derived from the Greek terms “eu,” meaning “good,” and “thanatos,” meaning “death”. A “good death” would be one that occurs without pain or distress. For the purpose of this
Suggested Revisions to Specific Euthanasia Methods
It was recommended that carbon dioxide be removed as an acceptable agent for the euthanasia of mink. Mass Euthanasia It was recommended that the AVMA Guidelines addressing mass euthanasia be expanded to include more information about euthanasia methods—by species— under various disease and disaster scenarios.
Policy on Rodent Euthanasia Via Euthanex Lid Administered Carbon Dioxide
Carbon dioxide (CO 2) is a frequently used euthanasia agent for small laboratory animals due to its rapid onset of action, safety, and ready availability. However, if not administered properly, CO 2 inhalation has the potential to cause pain and distress on1. All 2
POLICY #13.03 ANIMAL CARE AND USE COMMITTEE POLICY MANUAL Revised: 11.17.04 Euthanasia
- Injectable barbiturates can be used for euthanasia of fetuses and neonates. - Decapitation is acceptable for altricial rodents <7 days of age. - Cervical disloion can be used for both fetal and neonatal mice. 2. Carbon Dioxide Gas CO2 may cause distressa.